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Category: Viruses

Synthesis too slow? Let this robot do it. | MIT News
January 12, 2022

Researchers in the lab of Bradley Pentelute, MIT professor of chemistry, have invented a fully automated fast-flow instrument that can synthesize peptide-nucleic acids in a single shot. By automating the process of synthesizing CPP-conjugated peptide-nucleic acids (PPNAs) using the robot dubbed “Tiny Tides” by the research team, typical PPNA synthesis time was reduced from multiple days to just two hours. “This new...

Speeding up directed evolution of molecules in the lab | MIT News
December 30, 2021

Natural evolution is a slow process that relies on the gradual accumulation of genetic mutations. In recent years, scientists have found ways to speed up the process on a small scale, allowing them to rapidly create new proteins and other molecules in their lab. This widely-used technique, known as directed evolution, has yielded new antibodies to treat cancer and other diseases, enzymes used in biofuel production, and...

New 10-minute test detects Covid-19 immunity | MIT News
November 23, 2021

Researchers have successfully developed a rapid point-of-care test for the detection of SARS-CoV-2 neutralizing antibodies (NAbs). This simple test, only requiring a drop of blood from a fingertip, can be performed within 10 minutes without the need for a laboratory or specially trained personnel. Currently, no similar NAb tests are commercially available within Singapore or elsewhere. The work was led by the...

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